Author name: YASHASWINI N

WORLD THYROID DAY 2026 Thyroid disorders are a spectrum of conditions affecting the thyroid gland's hormone production and function, impacting metabolic rate and various bodily systems US Prevalence Global Prevalence ~200M < 12% ~60% undiagnosed rate Global incidence of thyroid disorders worldwide Female Male High Low Women are five to eight times more likely than men to have thyroid problems TYPES OF THYROID DISORDERS STAGES OF HASHIMOTO'S THYROIDITIS Hypothyroidism: Characterized by underactive thyroid; slow metabolism (e.g., Hashimoto's) Overt Hypothyroidism Hypothyroid Thyroid Strain Hyperthyroid Hyperthyroidism: Caused by overactive thyroid; fast metabolism (e.g., Graves' disease) Autoimmune Attack Autoimmune Priming Other Disorders: Nodule formation, goiter and thyroid cancer Metabolic rate Silent Triggers Hormone level (e.g., T4/T3) Iodine deficiency/excess SYMPTOMS OF HYPOTHYROIDISM Radiation exposure COMMON TRIGGERS Memory issues Dry skin Weight gain Cold intolerance SYMPTOMS OF HYPERTHYROIDISM Autoimmune (e.g., Hashimoto's) Genetics/Family history Weight loss Irritability Sweating Tremors DIAGNOSIS & TREATMENT First Line Second Line Liothyronine Desiccated thyroid extract Diagnosis challenge: Commonly misdiagnosed, with an average delay of 1-2 years Levothyroxine HYPOTHYROIDISM Radioactive iodine (RAI) Thyroid surgery Beta-blockers Methimazole Propylthiouracil (PTU) HYPERTHYROIDISM Clinical Interview Blood Tests Vitamin D Nodule monitoring Selenium supplements ADJUNCTIVE AND NODULE CARE Scans & Biopsy Thyroid Ultrasound Vyuhpharma® All Rights Reserved Note: This report is generated based on publicly available data

On World Thyroid Day, we raise awareness about thyroid health and its vital role in overall well-being. Early detection, education, and timely care can make a meaningful difference. Let’s continue supporting better health outcomes through awareness and action.

On World Thyroid Day, we raise awareness about thyroid health and its vital role in overall well-being. Early detection, education, and timely care can make a meaningful difference. Let’s continue supporting better health outcomes through awareness and action. Read More »

WORLD Schizophrenia Day 2026 Definition Schizophrenia is a serious mental illness that affects how a person thinks, feels, and behaves Global Prevalence US Prevalence 1.22 M 23.6 M People live with Schizophrenia worldwide New cases are diagnosed globally each year Prevalence of schizophrenia & related psychotic disorders 0.25% & 0.64% Late adolescence and the twenties, Earlier among men than among women 0% 0.1% 0.2% 0.3% 0.4% 0.5% Types of Schizophrenia Paranoid delusions focusing on the self Belief in being targeted by people, objects 'others'. Excitement & stupor phases Reluctance to move limbs/body Symptoms that don't clearly fit one of the other types Bizarre behavior, delusions & hallucinations Often occurs in adolescence Paranoid Catatonic Disorganized Undifferentiated Symptoms Positive Symptoms : any change in behaviour or thoughts Negative symptoms : often appear months or years before a person experiences delusions or hallucinations Positive Symptoms Delusions Confused thinking and speech Hallucinations Negative Symptoms Lack of Motivation Social Withdrawal Emotional Flatness Cognitive Symptoms Attention issues Problem-solving Impaired verbal ability Diagnosis > 2 of the specified symptoms according to DSM-5 classification for a duration of 1 month Recent update Clinical Interview for DSM-5 (SCID) How long symptoms have been appearing Rule out other possible illnesses Rule out substance use SNPs may now serve as biomarkers Treatment 1st Generation 2nd Generation New MOA MOA Typical mGPCR antagonists Atypical mGPCR antagonists M1/M4 agonist Drug Name Company Name Drug Name Company Name Drug Name Company Name Drugs Haloperidol Clozapine COBENFY Chlorpromazine Olanzapine Vyuhpharma® All Rights Reserved Note: This report is generated based on publicly available data

Today, we recognize Bipolar Disorder and Schizophrenia Awareness and stand in support of individuals, families, and communities affected by these conditions. By encouraging understanding, empathy, and open conversations, we can help reduce stigma and promote mental well-being for all.

Today, we recognize Bipolar Disorder and Schizophrenia Awareness and stand in support of individuals, families, and communities affected by these conditions. By encouraging understanding, empathy, and open conversations, we can help reduce stigma and promote mental well-being for all. Read More »

INFLAMMATORY BOWEL DISE SE IBD is an umbrella term for a group of conditions that cause swelling and inflammation of the tissues in the digestive tract Global Prevalence and Incidence Country-wise affected population Prevalence 2.4-3.1M 229.7 per 100,000 2.5-3 M Incidence Low Low with increase 0.18 M High TYPES OF IBD Crohn's disease Ulcerative colitis Crohn's disease (CD): It can affect any part of the digestive tract from mouth to anus and causes deep, tissue-layer inflammation Ulcerative colitis (UC): It affects only the colon and rectum's inner lining, causing inflammation and ulcers DIAGNOSIS Blood Test Stool Test Upper Endoscopy Colonoscopy Tissue Biopsy Imaging Studies Risk factors Causes of inflammatory Bowel Disease Medium Women face a higher risk of CD; men face a higher risk of UC Smoking affects development and severity of Crohn's Commonly diagnosed between ages 15-35 Luminal Factors Microbiome Intestinal Immune System Alterations Environmental Factor Genetic Predisposition SYMPTOMS Loss of appetite Fatigue Stomach aches and cramps Weight loss Diarrhea Blood in your stool TREATMENT Surgery Bowel resection Top-down approach Nutritional support Probiotics Biologic therapy Adalimumab & Infliximab Immunosuppressants Methotrexate, Azathioprine & Mercaptopurine Corticosteroids Budesonide, Methylprednisolone & Prednisolone 5-ASA | Antibiotics 5 ASA- Mesalamine & Sulfasalazine | Antibiotics- Ciprofloxacin & Metronidazole Step-up approach Vyuhpharma® All Rights Reserved Note: This report is generated based on publicly available data

True workplace inclusivity means supporting employees with chronic, often invisible conditions. Inflammatory Bowel Disease (IBD) affects millions of professionals worldwide, impacting daily life, energy and productivity.This World IBD Day, let’s advocate for understanding, flexible workplaces, and healthcare support. 💼💜

True workplace inclusivity means supporting employees with chronic, often invisible conditions. Inflammatory Bowel Disease (IBD) affects millions of professionals worldwide, impacting daily life, energy and productivity.This World IBD Day, let’s advocate for understanding, flexible workplaces, and healthcare support. 💼💜 Read More »

W rld Lupus Day 2026 Make Lupus Visible Definition: Lupus is a chronic autoimmune condition in which the body's immune system attacks its own tissues and organs Types of Lupus Systemic Lupus Erythematosus Cutaneous Lupus Drug-Induced Lupus Neonatal Lupus Most common type and affects multiple organs Mainly affects the skin Results from medications like Isoniazid, Procainamide and Hydralazine Rare, affects infants via maternal antibodies Prevalence (in 100,000 Population) Pathophysiology Genetic and environmental factors over-activate the immune system, using interferon to trigger T and B cells to produce harmful autoantibodies 160 120 80 40 Common Tiggers Air pollution Ultraviolet (UV) light Silica Dust Smoking Cigarettes Certain Medications Toxins Heavy Metals Diagnosis Complete Blood Count Erythrocyte Sedimentation Rate C-reactive Protein Test Kidney and Liver Tests Antinuclear Antibody Test Urine Tests Skin Biopsy Symptoms Sensitivity to Sun Purple Fingers /Toes Mouth Ulcers Headaches Butterfly rash Arthritis Fever Swelling of legs Pharmacological Treatment Socioeconomic burdens of lupus patients reaching $50,000 through medical expenses Generic Name Brand Name Company Name Hydroxychloroquine Sovuna & Plaquenil Prednisone Rayos 1 in 3 lupus patients suffers from multiple autoimmune diseases 9 out of 10 adults with lupus are women Most people develop the disease between the ages of 15-44 Voclosporin Lupkynis Anifrolumab-fnia Saphnelo Belimumab Benlysta Vyuhpharma® All Rights Reserved Note: This report is generated based on publicly available data

On World Lupus Day, we stand in support of everyone affected by lupus — raising awareness, encouraging early diagnosis, and advocating for better care and research. 💜Together, we can help improve lives through awareness, innovation, and compassion.

On World Lupus Day, we stand in support of everyone affected by lupus — raising awareness, encouraging early diagnosis, and advocating for better care and research. 💜Together, we can help improve lives through awareness, innovation, and compassion. Read More »

WORLD THALASSEMIA DAY HIDDEN NO MORE - Finding the Undiagnosed, Supporting the Unseen AN INHERITED HEMOGLOBIN DISORDER Thalassemia is a genetic condition caused by mutations in globin genes that lead to an imbalance of α- and β-globin chains, resulting in red blood cell destruction The 2026 Global Mission: To identify undiagnosed individuals and support those whose daily challenges remain unrecognized by society & healthcare systems Global Lighting Initiative "Bring To Light" movement encourages cities to illuminate iconic landmarks in red to symbolize solidarity and advocacy Alpha vs. Beta Thalassemia PREVALENCE Alpha Beta Alpha types involves deletions on chromosome 16 Beta types usually involve point mutations on chromosome 11 Minor vs. Major (TDT vs. NTDT) 1.3 M Global Cases Among them, 400,000 children are born with severe forms annually Mild Severe Minor/Trait Major/Transfusion-Dependent Often asymptomatic carriers Requires lifelong blood support for survival THALASSEMIA BELT REGIONS SYMPTOMS & COMPLICATIONS Chronic fatigue Pale skin Jaundice Shortness of breath Bone deformities Growth retardation THE TREATMENT REVOLUTION CASGEVY REBLOZYL Cell-based gene therapy Erythroid maturation agent The Danger of Iron Overload STANDARD CARE: TRANSFUSIONS & CHELATION Frequent transfusions can lead to iron accumulation, causing and organ damage Regular blood transfusions to maintain hemoglobin levels and iron chelation therapy to remove excess iron from the body Vyuhpharma® All Rights Reserved Note: This report is generated based on publicly available data

Every drop of awareness brings hope ❤️On World Thalassemia Day, we work together to create awareness on thalassemia, encourage early diagnosis and better access to care, and support patients and their families Together, we can help build a healthier and stronger future for every life affected by thalassemia

Every drop of awareness brings hope ❤️On World Thalassemia Day, we work together to create awareness on thalassemia, encourage early diagnosis and better access to care, and support patients and their families Together, we can help build a healthier and stronger future for every life affected by thalassemia Read More »

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