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Author name: YASHASWINI N

WORLD ASTHMA DAY MAY 5, 2026 BREATHE EASY , LIVE FULLY What Is Asthma? It is a chronic, non-communicable, inflammatory condition.That causes the airways in the lungs to swell, narrow, and produce extra mucus. ASTHMA CAN AFFECT ANYONE, AT ANY AGE 363M to 434M High Total Globally Approximately Prevalent in Children & Adolescents, Particularly Aged 5–9 and 10–17 Years, respectively 442L to 450L Total Mortality Low Adolescents Children 5–9 Yrs 10–17 Yrs Key Insight: Over 90% of deaths occur in low-to-middle income countries due to a lack of access to inhaled corticosteroids Low prevalence High prevalence Moderate prevalence Types of Asthma Allergic Asthma Non-Allergic Asthma Occupational Asthma Exercise-Induced Bronchoconstriction Cough-Variant Asthma Aspirin-Induced Asthma Common Tiggers Asthma Symptoms Air pollution Allergens Tobacco smoke Infection Physical activity Emotional stress Wheezing Shortness of Breath Chest Tightness Persistent Cough Key Management Strategy Microscopic View Healthy Airway Severe Asthma Airway smooth muscle: Hyperresponsiveness Constriction Thickening Early diagnosis and regular monitoring Adherence to prescribed medications Avoidance of known triggers Patient education awareness Asthma action plan Subepithelial inflammation and fibrosis Mucus hypersecretion and impaired mucus clearance Treatment Regimen Main Role Top Examples Medication Increased eosinophils and/or neutrophils in airway lumen Daily Controller (ICS) Prevents swelling/mucus Pulmicort, Arnuity, QVAR Combination (ICS+LABA) Long-term control + open airways Symbicort, Breo, Dulera AIR / MART Therapy One inhaler for daily use Symbicort (Budesonide/Formoterol) Quick Reliever (SABA) Immediate "emergency" relief Albuterol (Ventolin, ProAir) Add-on (LAMA/LTRA) Extra support for difficult symptoms Spiriva, Singulair Biologics Targeted injections for severe cases Dupixent, Tezspire, Exdensur Oral Steroids (OCS) Short-term "reset" for major flares Prednisone Bronchial Comparison Air trapped in alveoli Relaxed smooth muscles Tightened smooth muscles Wall inflamed and thickened Asthmatic airway during attack Normal airway Asthmatic airway

On World Asthma Day 2026, we stand for every breath, every life that matters.Asthma affects millions worldwide; yet, with the right awareness, early diagnosis and consistent care, it can be managed effectively.Let’s work together to create environments that support healthier lungs and better lives.

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On World Asthma Day 2026, we stand for every breath, every life that matters.Asthma affects millions worldwide; yet, with the right awareness, early diagnosis and consistent care, it can be managed effectively.Let’s work together to create environments that support healthier lungs and better lives. Read More »

World Parkinson’s Day 2026 Substantia nigra (Dopamine producing cells) Dopamine levels in normal neuron Parkinson’s disease (PD) is a neurodegenerative disorder that predominantly affects the dopamine-producing “dopaminergic” neurons, in specific area of the brain called the substantia nigra Lewy body inclusion Diffuse α-synuclein aggregates Motor Neuron Receiving neuron Transmitting neuron Dopamine receptor Dopamine Cellular Pathology Oligomerization α-synuclein monomer Mature Lewy body inclusion α-synuclein protofibril oligomer α-synuclein fibril aggregates Autocatalytic process Dopamine levels in PD affected neuron High PD symptoms Non-motor symptoms Motor symptoms 25.2M people with PD disease globally by 2050 Depression, anxiety, cognitive impairment Low Stooped posture Masked face Back rigidity Forward tilt Flexed elbows and wrists Loss of smell Prevalence of PD in the US Hand tremor Gastrointestinal symptoms M Flexed hip and knees W Tremors in legs 1.2M (2030) Americans will be living with PD 54% 46% 80+ 60-79 40-59 Joint pain Shuffling, short stepped gait (Age 80+) Age groups Clinical symptoms and time course of PD progression Early stages PD Diagnosis Advanced stages Prodromal period Impaired balance, functioning intact Both sides affected but balance remains One side of the body is affected Constipation RBD Walking and standing difficult without help Wheelchair-bound or bed-ridden -10 0 -20 10 20 PD management Diagnosis Symptomatic Treatment No Disease-modifying therapies (DMT) approved HIGH UNMNET NEED PERSISTS MAO-B inhibitors (MAOBi): Rasagiline, Selegiline Levodopa-Carbidopa: Standard fixed dose Prodrug formulations: Foslevodopa/ Foscarbidopa MRI PET scan SNCA LRRK2 GBA Blood & CSF Biomarkers MDS-UPDRS PDQ-39 "ON/OFF" Time Deep-Brain Stimulation (DBS) DBS for stronger symptom relief Neuroimaging Assessments Genetic tests Laboratory tests Vyuhgenics®, ISO 27001 & 9001 certified Note: This report is generated based on publicly available data

This World Parkinson’s Day, we stand united to amplify awareness and drive meaningful change. Parkinson’s is more than a condition—it’s a journey that impacts millions of lives. By supporting research, innovation, and compassionate care, we move one step closer to a better future. Together, let’s turn awareness into action.

Uncategorized /

This World Parkinson’s Day, we stand united to amplify awareness and drive meaningful change. Parkinson’s is more than a condition—it’s a journey that impacts millions of lives. By supporting research, innovation, and compassionate care, we move one step closer to a better future. Together, let’s turn awareness into action. Read More »

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