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Highlights from the Week of 20th April - 27th April FDA approves Sanofi's TZIELD sBLA to delay the onset of stage 3 type 1 diabetes in young children AstraZeneca's SAPHNELO Pen for self-administration gets FDA approval for the treatment of adult patients with SLE on top of standard therapy Regeneron receives accelerated approval from FDA for OTARMENI to treat patients with severe-to-profound and profound sensorineural hearing loss ( FDA, Accelerated Approval ) ( FDA, Approval ) ( FDA, Approval ) Pg 1/6 All logos and trademarks remain the intellectual properties of their respective owners

Highlights from the Week of 20th April – 27th April in the world of pharma and healthcare!

April 28, 2026

Highlights from the week of 13th April - 20th April Travere Therapeutics ( FDA, Approval ) Travere Therapeutics' FILSPARI gets FDA approval to reduce proteinuria in focal segmental glomerulosclerosis without nephrotic syndrome Alembic ( FDA, Approval ) Alembic gains FDA approval for methotrexate injection USP, 50 mg/2 mL (25 mg/mL) multi-dose vials & 1 g/40 mL (25 mg/mL) single-dose vials for the treatment of neoplastic diseases ARS Pharma ( Health Canada, Approval ) Health Canada approves ARS Pharma's NEFFY 2 mg for the emergency treatment of allergic reactions in those who weigh 30 kg or more, offering a new delivery method for epinephrine Merck ( FDA, Priority Review ) Merck receives Priority Review for ifinatamab deruxtecan, for the treatment of adult patients with extensive-stage small cell lung cancer All logos and trademarks remain the intellectual properties of their respective owners

Highlights from the Week of 13th April – 20th April in the world of pharma and healthcare!

April 20, 2026

Highlights from the Week of 6th April 2026 - 13th April 2026 ( Launch ) Ascendis Pharma launches the once-weekly YUVIWEL in the US for achondroplasia with open epiphyses to provide continuous systemic exposure to CNP ( EU, Approval ) EC grants approval to Sanofi and Regeneron's DUPIXENT, a IL4 and IL13 signal inhibitor to treat moderate-to-severe chronic spontaneous urticaria in children aged 2 to 11 years ( MHRA, Approval ) MHRA accepts Savara's MOLBREEVI application for marketing authorization indicated to treat autoimmune pulmonary alveolar proteinosis ( FDA, Fast Track ) Climb Bio obtains FDA Fast Track Designation for budoprutug, an anti-CD19 monoclonal antibody, for the treatment of primary membranous nephropathy Pg 1/2 All logos and trademarks remain the intellectual properties of their respective owners

Highlights from the Week of 6th April 2026 – 13th April 2026 in the world of pharma and healthcare!

April 13, 2026

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Investor calendar

INVESTOR CALENDER OF THE WEEK April 15,2026 To April 16,2026 Conference, HSBC Global Investment Summit, Hong Kong Needham 25th Annual Healthcare Conference Apr 15 Apr 15 Q1 2026 Earning Call Apr 16 All logos and trademarks remain the intellectual properties of their respective owners

Attention ⏰ Stay up to date with the latest investor calls by checking out our calendar for the week of April 15,2026 To April 16,2026

April 13, 2026

Annual general Meeting April 09,2026 April 09 All logos and trademarks remain the intellectual properties of their respective owners

Attention Stay up to date with the latest investor calls by checking out our calendar for the week of March April 09,2026

April 6, 2026

INVESTOR CALENDER OF THE WEEK March 24,2026 To March 26,2026 BNP Paribas Exane Healthcare Conference March 24 Goldman Sachs Biopharma Innovation Summit March 25 March 26 All logos and trademarks remain the intellectual properties of their respective owners

Attention Stay up to date with the latest investor calls by checking out our calendar for the week of March 24,2026 To March 26,2026

March 24, 2026

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Healthcare Insights

On World Lupus Day, we stand in support of everyone affected by lupus — raising awareness, encouraging early diagnosis, and advocating for better care and research. 💜Together, we can help improve lives through awareness, innovation, and compassion.

May 10, 2026

WORLD THALASSEMIA DAY HIDDEN NO MORE - Finding the Undiagnosed, Supporting the Unseen AN INHERITED HEMOGLOBIN DISORDER Thalassemia is a genetic condition caused by mutations in globin genes that lead to an imbalance of α- and β-globin chains, resulting in red blood cell destruction The 2026 Global Mission: To identify undiagnosed individuals and support those whose daily challenges remain unrecognized by society & healthcare systems Global Lighting Initiative "Bring To Light" movement encourages cities to illuminate iconic landmarks in red to symbolize solidarity and advocacy Alpha vs. Beta Thalassemia PREVALENCE Alpha Beta Alpha types involves deletions on chromosome 16 Beta types usually involve point mutations on chromosome 11 Minor vs. Major (TDT vs. NTDT) 1.3 M Global Cases Among them, 400,000 children are born with severe forms annually Mild Severe Minor/Trait Major/Transfusion-Dependent Often asymptomatic carriers Requires lifelong blood support for survival THALASSEMIA BELT REGIONS SYMPTOMS & COMPLICATIONS Chronic fatigue Pale skin Jaundice Shortness of breath Bone deformities Growth retardation THE TREATMENT REVOLUTION CASGEVY REBLOZYL Cell-based gene therapy Erythroid maturation agent The Danger of Iron Overload STANDARD CARE: TRANSFUSIONS & CHELATION Frequent transfusions can lead to iron accumulation, causing and organ damage Regular blood transfusions to maintain hemoglobin levels and iron chelation therapy to remove excess iron from the body Vyuhpharma® All Rights Reserved Note: This report is generated based on publicly available data

Every drop of awareness brings hope ❤️On World Thalassemia Day, we work together to create awareness on thalassemia, encourage early diagnosis and better access to care, and support patients and their families Together, we can help build a healthier and stronger future for every life affected by thalassemia

May 8, 2026

WORLD ASTHMA DAY MAY 5, 2026 BREATHE EASY , LIVE FULLY What Is Asthma? It is a chronic, non-communicable, inflammatory condition.That causes the airways in the lungs to swell, narrow, and produce extra mucus. ASTHMA CAN AFFECT ANYONE, AT ANY AGE 363M to 434M High Total Globally Approximately Prevalent in Children & Adolescents, Particularly Aged 5–9 and 10–17 Years, respectively 442L to 450L Total Mortality Low Adolescents Children 5–9 Yrs 10–17 Yrs Key Insight: Over 90% of deaths occur in low-to-middle income countries due to a lack of access to inhaled corticosteroids Low prevalence High prevalence Moderate prevalence Types of Asthma Allergic Asthma Non-Allergic Asthma Occupational Asthma Exercise-Induced Bronchoconstriction Cough-Variant Asthma Aspirin-Induced Asthma Common Tiggers Asthma Symptoms Air pollution Allergens Tobacco smoke Infection Physical activity Emotional stress Wheezing Shortness of Breath Chest Tightness Persistent Cough Key Management Strategy Microscopic View Healthy Airway Severe Asthma Airway smooth muscle: Hyperresponsiveness Constriction Thickening Early diagnosis and regular monitoring Adherence to prescribed medications Avoidance of known triggers Patient education awareness Asthma action plan Subepithelial inflammation and fibrosis Mucus hypersecretion and impaired mucus clearance Treatment Regimen Main Role Top Examples Medication Increased eosinophils and/or neutrophils in airway lumen Daily Controller (ICS) Prevents swelling/mucus Pulmicort, Arnuity, QVAR Combination (ICS+LABA) Long-term control + open airways Symbicort, Breo, Dulera AIR / MART Therapy One inhaler for daily use Symbicort (Budesonide/Formoterol) Quick Reliever (SABA) Immediate "emergency" relief Albuterol (Ventolin, ProAir) Add-on (LAMA/LTRA) Extra support for difficult symptoms Spiriva, Singulair Biologics Targeted injections for severe cases Dupixent, Tezspire, Exdensur Oral Steroids (OCS) Short-term "reset" for major flares Prednisone Bronchial Comparison Air trapped in alveoli Relaxed smooth muscles Tightened smooth muscles Wall inflamed and thickened Asthmatic airway during attack Normal airway Asthmatic airway

On World Asthma Day 2026, we stand for every breath, every life that matters.Asthma affects millions worldwide; yet, with the right awareness, early diagnosis and consistent care, it can be managed effectively.Let’s work together to create environments that support healthier lungs and better lives.

May 5, 2026

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