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Highlights from the week of 31st Aug - 07th Sep PharmaEssentia ( FDA, Approval ) FDA approves PharmaEssentia's BESREMi to treat adults with Essential Thrombocythemia, regardless of genotype or disease status Ionis ( FDA, Approval ) Ionis' ZANVASTRO gets FDA approval to treat Alexander disease in pediatric and adults patients AstraZeneca ( FDA, Approval ) FDA provides approval to AstraZeneca's ETCAMAH, in combination with CDK 4/6 inhibitor, to treat adults with HR-positive, HER2- negative, locally advanced or metastatic breast cancer AstraZeneca ( EU, Approval ) AstraZeneca's ENHERTU, in combination with pertuzumab, gets EU approval to treat adults with unresectable or metastatic HER2-positive breast cancer All logos and trademarks remain the intellectual properties of their respective owners

Highlights from the Week of 31st August – 07th September in the world of pharma and healthcare!

September 7, 2026

Highlights from the Week of 24th August 2026 - 31st August 2026 ( US, Launch ) Cycle Pharma launches CAVHANZA in the US to offer dosing flexibility and tolerability for patients with Ph+ CML ( EU, Launch ) Celltrion launches OMLYCLO 300 mg PFS and AI presentations in key European markets for CSU and allergic asthma ( FDA, Approval ) J&J receives approval from the FDA for IMAAVY to treat wAIHA in patients aged 12 and older ( FDA, Approval ) Jazz Pharmaceuticals gets FDA approval for ZIIHERA regimens to treat adults with unresectable locally advanced or metastatic HER2+ gastroesophageal adenocarcinoma Pg 1/5 All logos and trademarks remain the intellectual properties of their respective owners

Highlights from the Week of 24th August – 31st August in the world of pharma and healthcare!

August 31, 2026

Highlights from the week of 17th Aug - 24th Aug Biocon ( FDA, Approval ) Biocon receives approval from FDA for YESINTEK 45 mg/0.5 mL and 90 mg/mL single-dose prefilled autoinjectors to treat adult and pediatrics with psoriasis, and adults with CD and UC Regeneron ( FDA, Approval ) Regeneron gets FDA approval for PASATRU, indicated to reduce the formation of new HO lesions and clinician-assessed flare-ups in adults with FOP Ultragenyx ( FDA, Accelerated Approval ) FDA grants accelerated approval for Ultragenyx's DTX401, indicated to treat GSDIa in adults and pediatrics Johnson&Johnson ( EU, Approval ) J&J receives indication extension approval from EC for TECVAYLI in combination with daratumumab to treat adults with RRMM who received at least one prior therapy All logos and trademarks remain the intellectual properties of their respective owners

Highlights from the Week of 17th August – 24th August in the world of pharma and healthcare!

August 24, 2026

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Investor calendar

Q2 2026 earnings conference Call Aug 03,2026 To Aug 06,2026 Aug 03 Aug 04 Aug 05 Aug 06 All logos and trademarks remain the intellectual properties of their respective owners

Attention stay up to date with the latest investor calls by checking out our calendar for the week of August 03,2026 To August 06,2026

August 3, 2026

Q2 2026 Earnings Conference Call Jul 27,2026 To Jul 31,2026 Jul 29 Jul 28 Jul 27 JUl 30 Jul 31 All logos and trademarks remain the intellectual properties of their respective owners

Attention stay up to date with the latest investor calls by checking out our calendar for the week of July 27,2026 To July 31,2026

July 27, 2026

2026 RBC Capital Markets Global Healthcare Conference Q2 2026 Earnings Call July 21,2026 To July 23,2026 July 23 July 21 All logos and trademarks remain the intellectual properties of their respective owners

Attention stay up to date with the latest investor calls by checking out our calendar for the week of July 21,2026 To July 23,2026

July 20, 2026

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Healthcare Insights

On World Lupus Day, we stand in support of everyone affected by lupus — raising awareness, encouraging early diagnosis, and advocating for better care and research. 💜Together, we can help improve lives through awareness, innovation, and compassion.

May 10, 2026

WORLD THALASSEMIA DAY HIDDEN NO MORE - Finding the Undiagnosed, Supporting the Unseen AN INHERITED HEMOGLOBIN DISORDER Thalassemia is a genetic condition caused by mutations in globin genes that lead to an imbalance of α- and β-globin chains, resulting in red blood cell destruction The 2026 Global Mission: To identify undiagnosed individuals and support those whose daily challenges remain unrecognized by society & healthcare systems Global Lighting Initiative "Bring To Light" movement encourages cities to illuminate iconic landmarks in red to symbolize solidarity and advocacy Alpha vs. Beta Thalassemia PREVALENCE Alpha Beta Alpha types involves deletions on chromosome 16 Beta types usually involve point mutations on chromosome 11 Minor vs. Major (TDT vs. NTDT) 1.3 M Global Cases Among them, 400,000 children are born with severe forms annually Mild Severe Minor/Trait Major/Transfusion-Dependent Often asymptomatic carriers Requires lifelong blood support for survival THALASSEMIA BELT REGIONS SYMPTOMS & COMPLICATIONS Chronic fatigue Pale skin Jaundice Shortness of breath Bone deformities Growth retardation THE TREATMENT REVOLUTION CASGEVY REBLOZYL Cell-based gene therapy Erythroid maturation agent The Danger of Iron Overload STANDARD CARE: TRANSFUSIONS & CHELATION Frequent transfusions can lead to iron accumulation, causing and organ damage Regular blood transfusions to maintain hemoglobin levels and iron chelation therapy to remove excess iron from the body Vyuhpharma® All Rights Reserved Note: This report is generated based on publicly available data

Every drop of awareness brings hope ❤️On World Thalassemia Day, we work together to create awareness on thalassemia, encourage early diagnosis and better access to care, and support patients and their families Together, we can help build a healthier and stronger future for every life affected by thalassemia

May 8, 2026

WORLD ASTHMA DAY MAY 5, 2026 BREATHE EASY , LIVE FULLY What Is Asthma? It is a chronic, non-communicable, inflammatory condition.That causes the airways in the lungs to swell, narrow, and produce extra mucus. ASTHMA CAN AFFECT ANYONE, AT ANY AGE 363M to 434M High Total Globally Approximately Prevalent in Children & Adolescents, Particularly Aged 5–9 and 10–17 Years, respectively 442L to 450L Total Mortality Low Adolescents Children 5–9 Yrs 10–17 Yrs Key Insight: Over 90% of deaths occur in low-to-middle income countries due to a lack of access to inhaled corticosteroids Low prevalence High prevalence Moderate prevalence Types of Asthma Allergic Asthma Non-Allergic Asthma Occupational Asthma Exercise-Induced Bronchoconstriction Cough-Variant Asthma Aspirin-Induced Asthma Common Tiggers Asthma Symptoms Air pollution Allergens Tobacco smoke Infection Physical activity Emotional stress Wheezing Shortness of Breath Chest Tightness Persistent Cough Key Management Strategy Microscopic View Healthy Airway Severe Asthma Airway smooth muscle: Hyperresponsiveness Constriction Thickening Early diagnosis and regular monitoring Adherence to prescribed medications Avoidance of known triggers Patient education awareness Asthma action plan Subepithelial inflammation and fibrosis Mucus hypersecretion and impaired mucus clearance Treatment Regimen Main Role Top Examples Medication Increased eosinophils and/or neutrophils in airway lumen Daily Controller (ICS) Prevents swelling/mucus Pulmicort, Arnuity, QVAR Combination (ICS+LABA) Long-term control + open airways Symbicort, Breo, Dulera AIR / MART Therapy One inhaler for daily use Symbicort (Budesonide/Formoterol) Quick Reliever (SABA) Immediate "emergency" relief Albuterol (Ventolin, ProAir) Add-on (LAMA/LTRA) Extra support for difficult symptoms Spiriva, Singulair Biologics Targeted injections for severe cases Dupixent, Tezspire, Exdensur Oral Steroids (OCS) Short-term "reset" for major flares Prednisone Bronchial Comparison Air trapped in alveoli Relaxed smooth muscles Tightened smooth muscles Wall inflamed and thickened Asthmatic airway during attack Normal airway Asthmatic airway

On World Asthma Day 2026, we stand for every breath, every life that matters.Asthma affects millions worldwide; yet, with the right awareness, early diagnosis and consistent care, it can be managed effectively.Let’s work together to create environments that support healthier lungs and better lives.

May 5, 2026

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